Uniswap COO Mary-Catherine Lader Resigns
Mary-Catherine Lader, president and chief operating officer of decentralized trading platform Uniswap Labs, has resigned from her position after four years with the company.
According to a Bloomberg report, Lader will serve in an advisory role ahead of moving on to a new venture. A spokesperson for Uniswap stated that the company “will continue to build on her contributions.”
Lader joined Uniswap in 2021 from investment giant BlackRock, where she held significant roles including managing director and global head of Aladdin Sustainability. Her transition from traditional finance to cryptocurrency was among the most notable early moves in the sector.
“Personal news: after four incredible years as President & COO of @Uniswap, I’m starting something new.
This is a new chapter for crypto. We’ve come a long way since I started digital assets at BlackRock in 2015. Building with Hayden was an awesome adventure.”
— Mary-Catherine Lader (@Mclader) July 15, 2025
Uniswap, Ethereum’s largest decentralized exchange protocol, remains a cornerstone of the cryptocurrency ecosystem following Lader’s departure. Founded by Hayden Adams in 2018, the platform facilitates peer-to-peer token swaps without intermediaries.
Unlike centralized exchanges such as Coinbase, Binance and Kraken, Uniswap enables users to directly trade tokens. Over the past 30 days, the platform’s trading volume reached $73 billion according to DefiLlama data.
Lader’s Legacy at Uniswap
During her tenure as president and COO, Lader oversaw the development of Uniswap’s internal infrastructure across finance, legal, human resources, marketing and customer support, transforming the developer-centric startup into a structured organization.
In October 2022, Uniswap raised $165 million at a valuation of approximately $1.66 billion.
Earlier this year, the SEC closed an investigation related to crypto trading activities dating back to a 2024 Wells Notice without taking enforcement action.
